Clinical Research in the Northwest
Why bother to participate in clinical trials and observational studies? Because, without participation we will never have new treatments for Huntington's.
- Current or Upcoming Clinical Trials
- Current or Upcoming Observational and Clinical Research Studies
- Previous Clinical Research Results
|Reach2HD, an on-going clinical trial at Evergreen Neuroscience Center testing a new drug for Huntington’s disease is now closed for enrollment. Though the Northwest had a very short time period for enrolling participants, we had 6 accepted into the trial. Thank you to all participants, and to Evergreen for for it's clinical trial efforts for Huntington's disease.|
|For symptomatic HD individuals: This is a Phase 3 clinical trial that is testing whether high dose creatine can slow disease progression for those diagnosed with HD. Creatine is a nutritional supplement that has shown benefit in some HD mouse models. Potential benefit for individuals with HD has been suggested in earlier Phase 2 study (for safety and dosage testing) performed in Boston where decreased brain atrophy was shown for those individuals who took high dose creatine. This is a 3-year clinical trial. For full description visit www.hdtrials.org or www.clinicaltrials.gov.
||This Clinical trial, which is testing the effect of high dose Co-Enzyme Q-10 on slowing progression of disease in symptomatic individuals is offered in Boise, Idaho
Observational and Clinical Research Studies
|The purpose of this study is to learn more about the diagnosis and progress of Huntington's Disease (HD). We are asking people over the age of 18 years, who have the gene for HD, but have not had an abnormal neurological examination, to take part in this study. We are also asking people who were at risk for HD but do not carry the gene (gene negative) to participate, for purposes of comparison. We will use paper-and-pencil tests, computer test, brain scans (MRI), blood and urine tests, and examinations by a doctor, to learn what happens as people move from health to HD.
|Enroll-HD study is a new international study that involves North America, Europe, South America and parts of Asia. Data from those of you who have already contributed to COHORT (with your permission) will added to Enroll-HD.
This study is an active collaboration of HD patients, individuals born at risk for HD (regardless of whether they have been tested genetically), and their families. It requires about a half day visit once a year. This study is vital to the more rapid development of treatments for HD therapeutics and completion of clinical trials. Visit EnrollHD.org for more information and updates.
Transportation reimbursement available.
Previous Clinical Research Results
|This phase 2 trial has been completed and gave a positive signal of benefit for motor symptoms. A Phase 3 trial trial is planned for 2012.|
|Dimebon Phase 3
|Unfortunately this trial showed no benefit in Huntington’s or Alzheimer’s disease.|